导师信息#华中农业大学水产学院导师介绍#林蠡

林蠡[教授]

姓名林蠡性别男职称教授学位博士电话027-87282113邮箱linli@mail.hzau.edu.cn工作单位华中农业大学水产学院水生动物医学系研究方向水生动物疾病学；水生动物免疫学；水环境调控；耐药性；免疫增强剂、疫苗与药物研发教育经历1998.09-2004.12 ，中山大学，动物学
，博士
2002.09-2004.09，汉堡大学（德国) ，动物学
，博士生
2001.09-2002.08，同济大学 ，德语
，学习
1991.09-1994.07，华南师范大学 ，动物学
，硕士
1987.09-1991.07，中国海洋大学 ，水产养殖
，学士主要职历2012.12-至今，华中农业大学 ，湖北省“楚天学者 ”特聘教授，博士生导师
2009.11-2012.11
，U.ofSaskatchewan(加拿大)，博士后
2008.02-2009.10 ，RiceUniversity（美国）
，博士后
2005.07-2008.01，PennsylvaniaStateUniversity（美国） ，博士后
2000.07-2000.12
，日本国立渔业研究所，鱼病研修
2004.10-2005.06 ，广东省海洋与渔业局技术推广部
，副部长，增殖科科长
1998.08-2004.09 ，广东省大亚湾水产试验中心
，海水养殖，病害部主任
1994.07-1998.07 ，广东省西江水产资源增殖中心，淡水养殖
，场长
科研成果发表文章60多篇，其中SCI文章40多篇；国际专利2项 ，国内专利1项；参编专著2部 。主要代表作如下（带*号为通信作者
，带+号为共同第一作者）:YachanJi+,JinquanLi+,ZhendongQin,AihuaLi,ZemaoGu,XiaolingLiu,LiLin,YangZhou*.ContributionofnucleasetothepathogenesisofAeromonashydrophila.Virulence,2015,accepted.SCIIF:3.319.FeifeiZheng,MuhammadAsim,JiangfengLan,LijuanZhao,ShunWei,NanChen,XiaolinLiu,YangZhou*,LiLin*.Daniorerio)duringInfectionwithAeromonasSobria.MolecularCloningandFunctionalCharacterizationofMannoseReceptorinZebraFish(InternationalJournalofMolecularSciences,2015,16:10997-10112.SCIIF:2.3XianqinHu,XiaozheFu,NingqiuLi*,XingxingDong,LijuanZhao,JiangfengLan,WeiJi,WeidongZhou,TaoshanAi,ShuqinWu,LiLin*.TranscriptomicanalysisofMandarinfishbraincellsinfectedwithinfectiousspleenandkidneynecrosisviruswithanemphasisonretinoicacid-induciblegene1-likereceptorsandapoptosispathways.FishandShellfishImmunology,2015,45:619-629.SCIIF:3.0.（JCR一区）DongX,QinZ,HuX,LanJ,YuanG,AsimM,ZhouY,AiT,MeiJ*,LinL*.MolecularcloningandfunctionalcharacterizationofcyclophilinAinyellowcatfish(Pelteobagrusfulvidraco).FishandShellfishImmunology,2015,45:422-430.SCIIF:3.0.（JCR一区）LiL,LuoY,GaoZ,HuangJ,ZhengX,NieH,ZhangJ,LinL,YuanJ.MolecularcharacterisationandprevalenceofanewgenotypeofCyprinidherpesvirus2inmainlandChina.CanJMicrobiol.2015,13:1-7.SCIIF:1.2.WenjunXu,ZhendongQin,HuiShi,NanJiang,YangZhou,XiaolingLiu,JianjunXie,GenshenWang,WeiminWang,MuhammadAsim,LingbingZeng,LiLin*.Massmortalityassociatedwithaviral-inducedanaemiaincage-rearedlargeyellowcroaker,Larimichthyscrocea(Richardson).JournalofFishDiseases,2015;38(5):499-502.SCIIF:1.5.（JCR二区）XiaodanLiu,JiannanHuang,ShaopingWeng,XianqinHu,WenjieChen,ZhendongQin,XingxingDong,XiaolingLiu,YangZhou,MuhammadAsim,WeiminWang,JianguoHe*,LiLin*.Infectionsofnervousnecrosisvirusinwildandcage-rearedmarinefishfromSouthChinaSeawithunexpectedwidehostranges.JournalofFishDiseases,2015;38(6):533-40.SCIIF:1.5.（JCR二区）WenwenWang,MuhammadAsim,LizhuYi,AbeerMHegazy,XianqinHu,YangZhou,TaoshanAi,LiLin*.AbortiveinfectionofsnakeheadfishvesiculovirusinZF4cellswasassociatedwiththeRLRspathwayactivationbyviralreplicativeintermediates.InternationalJournalofMolecularSciences,2015;16(3):6235-50.SCIIF:2.3XiaodanLiu,YiWen,XianqinHu,WenwenWang,XufangLiang,JunLi,VikramVakharia,LiLin*.Breakingthehostrange:Mandarinfishwassusceptibletoavesiculovirusderivedfromsnakeheadfish.JournalofGeneralVirology,2015;96(Pt4):775-81.SCIIF:3.5.XiaohengZhao,LichunLiu,AbeerM.Hegazy,HongWang,JieLi,FeifeiZheng,YangZhou,WeiminWang,JunLi,XiaolingLiu*,LiLin*.Mannosereceptormediatedphagocytosisofbacteriainmacrophagesofbluntsnoutbream(Megalobramaamblycephala)inaCa2+-dependentmanner.FishandShellfishImmunology,2015;43(2):357-363,SCIIF:3.0.（JCR一区）WeidongZhou,YuleiZhang,YiWen,WeiJi,YangZhou,YachanJi,XiaolingLiu,WeiminWang,MuhammadAsim,XufangLiang*,TaoshanAi*,LiLin*.AnalysisofthetranscriptomicprofilingsofMandarinfish(Sinipercachuatsi)infectedwithFlavobacteriumcolumnarewithanemphasisonimmuneresponses.FishShellfishImmunol.2015;43(1):111-119,SCIIF:3.0.（JCR一区）TranNT,GaoZX,ZhaoHH,YiSK,ChenBX,ZhaoYH,LinL,LiuXQ,WangWM*.Transcriptomeanalysisandmicrosatellitediscoveryinthebluntsnoutbream(Megalobramaamblycephala)afterchallengewithAeromonashydrophila.FishandShellfishImmunology,2015,45:72-82.SCIIF:3.0（JCR一区）GuangxinLiu,LiLin,MinWang,XueqinLiu*.Developmentandevaluationofaloop-mediatedisothermalamplificationassayforthedetectionofchannelcatfishvirus.JournalofFishDiseases,2015,Accepted.SCIIF:1.7.（JCR二区）LiuL,ZhuB,WuS,LinL,LiuG,ZhouY,WangW,AsimM,YuanJ,LiL,WangM,LuY,WangH,CaoJ,LiuX*.SpringViremiaofCarpVirusInducesAutophagyforNecessaryViralReplication.CellMicrobiol.2015,17:595-605.SCIIF:4.8.WuS,LiuL,ZohaibA,LinL,YuanJ,WangM,LiuX*.MicroRNAprofileanalysisofEpitheliomapapulosumcyprinicelllinebeforeandafterSVCVinfection.DevCompImmunol.2015,48(1):124-8.SCIIF:3.7.（JCR二区）LiLin*,WeiminWang*.Lung-KidneyDualFunctionsofFishGill.AnnalsofAquacultureandResearch.2014,1(1):1003.YuanJ,YangY,NieH,LiL,GuW,LinL,ZouM,LiuX,WangM,GuZ*.TranscriptomeanalysisofepitheliomapapulosumcyprinicellsafterSVCVinfection.BMCGenomics.2014,15:935.SCIIF:4.0LiuL,ZhouY,ZhaoX,WangH,WangL,YuanG,AsimM,WangW,ZengL,LiuX*,LinL*.Oligochitosanstimulatedphagocyticactivityofmacrophagesfrombluntsnoutbream(Megalobramaamblycephala)associatedwithrespiratoryburstcoupledwithnitricoxideproduction.DevCompImmunol.47(1):17-24,2014.SCIIF:3.7.（JCR二区）WangL,LiuL,ZhouY,ZhaoX,XiM,WeiS,FangR,JiW,ChenN,GuZ,LiuX,WangW,AsimM,LiuX*,LinL*,MolecularcloningandexpressionanalysisofmannosereceptorCtype1ingrasscarp(Ctenopharyngodonidella),DevCompImmunol,2014;43(1):54-8.SCIIF:3.7.（JCR二区）XiaolingLiu,XiaochengTang,LiWang,JieLi,HongWang,ShunWei,RuiFang,WeiJi,GailingYuan,NanChen,ZemaGu,XueqinLiu,WeiminWang,MuhammadAsim,YangZhou*,LiLin*.Molecularcloningandexpressionanalysisofmannosereceptorinbluntsnoutbream(Megalobramaamblycephala).MolecularBiologyReports.2014;41(7):4601-11.SCIIF:2.5.LiQ,LiuL,LinL,LiZ,LiuG,WuS,WangM,LiL,YuanJ,YuanG,LiuX*.ImmunizationwithrecombinantbaculovirusexpressingtheVP6proteinofgrasscarpreovirusinducesimmunityingrasscarp.VirolSin.2014,29(4):261-3YangY,HuangJ,LiL,LinL,ZhaiY,ChenX,LiuX,WuZ,YuanJ*.Up-regulationofnuclearfactorE2-Relatedfactor2uponSVCVinfection.FishShellfishImmunol.17;40(1):245-252,2014.SCIIF:3.0（JCR一区）LuoYZ,LinL,LiuY,WuZX,GuZM1,LiLJ*,YuanJF*.HaematopoieticNecrosisofCulturedSilverPrussianCarp(Carassiusgibelio)AssociatedwithCyprinidHerpesvirus.JournalofFishDiseases,36(12):1035-1039,2013.SCIIF:2.0.（JCR二区）LiyueLiu,QinLi,LiLin,MinWang,YuananLu,WeiminWang,JunfaYuan,LijuanLi,XueqinLiu*.Proteomicanalysisofepitheliomapapulosumcyprinicellsinfectedwithspringviraemiaofcarpvirus.FishandShellfishImmunology,35(1):26-35,2013.SCIIF:3.0（JCR一区）Hyun-MiPyo,AlexMasic,NizihtiWoldeab,CarissaEmbury-Hyatt,LiLin,Yeun-KyungShin,Jae-YoungSong,ShawnBabiukandYanZhou*.PandemicH1N1influenzaviruslikeparticlesareimmunogenicandprovideprotectiveimmunitytopigs.Vaccine,30:1297-1304,2012.SCIIF:3.5.（JCR二区）LiLin,QiangLiu,NathalieBerube,YanZhou*.5’-triphosphate-siRNA:potentinhibitionofinfluenzaAvirusinfectionbygenesilencingandRIG-Iactivation.JournalofVirology,86:10359-10369,2012.SCIIF:5.4.（JCR二区）LiLin,YangLi,Hyun-MiPyo,XinyaLu,SathyaNarayanan,QiangLiuandYanZhou*.IdentificationofRNAhelicaseAasacellularfactorthatinteractswithinfluenzaANS1proteinanditsroleinviruslifecycle.JournalofVirology,86：1942-1954,2012.SCIIF:5.4.（JCR二区）RajeevBoregowda,LiLin,LaurieLudgate1,QinZhu,FangTian,andJianmingHu*.CrypticproteinprimingsitesintwodifferentdomainsofduckhepatitisBvirusreversetranscriptaseforinitiatingDNAsynthesisinvitro.JournalofVirology,85:7754-7765,2011.SCIIF:5.4.（JCR二区）JunhuaPan*,LiLin*,YizhiJaneTao.Self-guanylylationofbirnavirusVP1doesnotrequireanintactpolymeraseactivitysite.Virology,2009,395(1):87-96.(*contributedequally).SCIIF:3.2.（JCR二区）PanJ,DongL,LinL,OchoaWF,SinkovitsRS,HavensWM,NibertML,BakerTS,GhabrialSA,TaoYJ,AtomicstructurerevealstheuniquecapsidorganizationofadsRNAvirus.ProcNatlAcadSciUSA.2009,106(11):4225-30.SCIIF:9.43.（JCR一区）JianmingHuandLiLin.RNA-proteininteractionsinhepadnavirusreversetranscription.FrontBiosci.2009,1;14:1606-18.SCIIF:3.7.LiLin,F.Wan,andJHu,FunctionalandStructuraldynamicsofHepadnavirusReverseTranscriptaseDuringProtein-PrimedInitiationofReverseTranscription:EffectsofMetalIons.JournalofVirology,2008,82:5703-5714.SCIIF:5.4.（JCR二区）LiLinandHu,J.InhibitionofHepadnavirusReverseTranscriptase-εRNAInteractionbyPorphyrinCompounds.Journalofvirology,2008,82:2305-2312.SCIIF:5.4.（JCR二区）HuangJ.N.*,LinL.*,S.P.WengandJ.G.He.Highexpressionofcapsidproteinofred-spottedgroupernervousnecrosisvirusinanaviancelllinerequiresviralRNA2non-codingregions.JournalofFishDiseases,2007,30:439-444(*contributedequally).SCIIF:1.7.（JCR二区）MatthesE,A.Funk,I.Krahn,K.Gaertner,M.vonJanta-Lipinski,L.Lin,H.Will,H.Sirma.StrongandSelectiveInhibitorsofHBV-ReplicationBetweenNovelN4-Hydroxy-and5-Methyl-beta-L-deoxycytidineAnalogues.AntimicrobAgentsChemother.2007,51:2523-2530.SCIIF:4.8.（JCR二区）LiLin,AlexPrassolov,AnnkeFunk,HansWill,HueseyinSirmaetal.Evidencefromnature:interspeciesspreadofavianhepatitisBviruses.JournalofGeneralVirology，200586:1335-42.SCIIF:3.4.AnnekaFunk,LiLin,MounaMhamdi,HansWill,HueseyinSirma.DeterminantsofHepadnaviralSpeciesandLiverCellTropism.MonogrVirol.Basel,Karger,2005,25:56-65.Sirma,H.,A.Funk,H.Hohenberg,M.Petrimpol,M.Mhamdi,L.Lin,U.Schubert,H.Will.Functionalmodulationofvirus-cellinteractionsbydrugs:newconceptsfortreatmentofviralhepatitisandhepatocellularcarcinoma.In:Proc.11thInternationalSymposiumonViralHepatitisandLiverDisease.Sydney,Australia(eds:A.R.Jilbertetal.),AustralianCentreforHepatitisVirologyPublisher,ISBN1877040266,2004:293-296.AnnekeFunk,MounaMhamdi,LiLin,HansWill,HueseyinSirma.ItineraryofHepatitisBViruses:DelineationofRestrictionPoints.Journalofvirology,2004,78:8289-8300.SCIIF:5.4.（JCR二区）LiLin,HeJG,MoriK,etal.Massmortalitiesassociatedwithviralnervousnecrosisinhatchery-rearedgroupersinthePeople’sRepublicofChina.FishPathology,2001,36:186-188.SCIIF:1.07.陈文捷 ，刘晓丹
，胡先勤，王文文 ，秦真东
，王瑶，周洋 ，刘小玲
，林蠡*.鱼类神经坏死病毒研究进展与发展趋势.水产学报，2014 ，38:1666-1670.刘晓丹，胡先勤
，黄剑南，翁少萍 ，王文文
，陈文捷，秦真东 ，董星星
，周洋，刘小玲 ，张学振
，郭志勋，何建国* ，林蠡*.原位杂交和免疫荧光检测鱼类神经坏死病毒在宿主鱼组织中的分布.水生生物学报
，2014，38(5)：876-882.黄剑南 ，郭志勋，冯娟
，林蠡*.鱼类诺达病毒及其所导致的疾病.水产学报，2006 ，30(6)：831-836.林蠡
，黄剑南，翁少萍 ，王云新
，刘付永忠，张海发 ，何建国.赤点石斑鱼病毒性神经坏死症的组织病理和电镜观察.水产学报
，2005，29（4）：519-523.

Beta-L-nucleosidesandtheiruseaspharmaceuticalagentsandtheirusefortherapyofviraldiseases.US2006/0217345A1,Worldpatent,WO2005/026186A1.美国和德国专利

HusbandryandHealthManagementofGrouper.Asia-PacificEconomicCooperationFisheriesWorkingGroup01,2000:1-94.（石斑鱼的培育和健康养殖 ，亚太经贸组织渔业工作组01
，2000:1-94.）

《中国海洋鱼类单殖吸虫》，张剑英等 ，中国农业出版社，2001：1-400。


备注获广东省科技一等奖；德国学术交流中心（DAAD）奖学金获得者；获国家自然科学基金面上项目 、湖北省科技支撑计划项目、高校业务专项基金等资助
。为《水产学报》编委
，InternationalJournalofMolecularSciences(5年平均SCI=2.7)客座编委。多种国际期刊审稿人，包括FishandShellfishImmunology,Aquaculture等刊物 。欢迎对水生动物病害与免疫感兴趣的学生加盟
。

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