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来源：河北大学 2019-08-19 相关院校：河北大学

河北大学化学与环境科学院研究生导师王克让介绍如下：

一、个人简介

王克让，男，1979年，南开大学刘宇教授(2006~2009年)，郑州大学张艳冰教授(2003~2006年)，2009年在河北大学工作，主要从事功能超分子纳米组装体的结构和识别研究，基于生物效应的荧光传感研究和抗肿瘤化合物的合成和作用机制研究。目前主持国家

家庭自然科学基金和河北自然科学基金等8项。2016年获河北省优秀青年基金。2016年入选河北省“三三三人才工程”三级候选人。在Adv. Funct. Mater., Chem. Commun., ACS Macro Lett., Chem. Eur. J.还有Biosens. Bioelectron.发表论文30多篇，授权发明专利6项。

联系方式：kerangwang@163.com

二、讲座课程及研究方向

1. 主课：有机化学

2. 研究方向：超分子化学、化学生物学

三、代表性论文

1) Chun-Miao Zhao, Ke-Rang Wang*, Chong Wang, Xu He, Xiao-Liu Li*. Cooling-induced NIR emission enhancement and targeting fluorescence imaging of bi-perylene monoimide and glycodendrimer conjugates. ACS Macro Lett., 2019, 8, 381-386.

2) Jiu-Kai Xiong, Ke-Rang Wang,* Kai-Xin Wang, Tian-Lei Han, Hong-Yu Zhu, Rui-Xue Rong, Zhi-Ran Cao, Xiao-Liu Li*. Fluorescent enhancement sensing of Cadmium (II) ion based on a perylene bisimide derivative. Sens. Actuators B Chem., 2019, 297, 126802.

3) Juan-Juan Li, Ke-Rang Wang*, Ren-Feng Li, Jian-Xing Yang, Min Li, Hong-Xin Zhang, Zhi-Ran Cao, Xiao-Liu Li*. Synthesis, self-assembly behaviours and multivalent glycosidase inhibition effect of deoxynojirimycin modified perylene bisimide derivatives. J. Mater. Chem. B, 2019, 7, 1270-1275.

4) Min Li, Ke-Rang Wang*, Jian-Xing Yang, Ya-Tong Peng, Yi-Xuan Liu, Hong-Xin Zhang, Xiao-Liu Li*. Supramolecular azasugar clusters based on an amphiphilic fatty-acid-deoxynojirimycin derivative as multivalent glycosidase inhibitors. J. Mater. Chem. B, 2019, 7, 1379-1383.

5) Xiao Chen, Ya-Nan Wang, Rui-Xue Rong, Chun-Miao Zhao, Xiao-Liu Li*, Ke-Rang Wang*. Synthesis, thermos-responsive behavior of cyclodextrin modified bi-perylene monoimide derivative. Dyes Pigments, 2019, 160, 779-786.

6) Qi Xu, Jia-Li Wang, Ya-Li Luo, Juan-Juan Li, Ke-Rang Wang*, Xiao-Liu Li*. Host-guest interactions and controllable capture and release of proteins based on cationic perylene bisimides. Chem. Commun., 2017, 53, 2241-2244.

7) Guo-Jing Cao, Rui-Xue Rong, Ya-Nan Wang, Qi Xu, Ke-Rang Wang*, Xiao-Liu Li*. Synthesis and Photodynamic therapy of Mono-mannose Modified Perylene Bisimide Bridged Permethyl-b-CDs. Dyes Pigments, 2017, 136, 569-576.

8) Ke-Rang Wang*, Zi-Bo Yang, Xiao-Liu Li*. High excimer-state emission of perylene bisimides and its recognition of latent fingerprints. Chem. Eur. J., 2015, 21, 5680-5684. (Frontispieces)

9) Ke-Rang Wang*, Dan Han, Guo-Jing Cao, Xiao-Liu Li*.Synthesis and predetermine supramoecular chirality of carbohydrates functionalized perylene bisimide derivatives. Chem. Asian J., 2015, 10, 1204-1214.

10)Ke-Rang Wang*, Hong-Wei An, Rui-Xue Rong, Zhi-Ran Cao, Xiao-Liu Li*. Synthesis of biocompatible glycodendrimer based on fluorescent perylene bisimides and its bioimaging. Macromol. Rapid. Commun., 2014, 35, 727-734.

11) Ke-Rang Wang*, Hong-Wei An, Rui-Xue Rong, Zhi-Ran Cao, Xiao-Liu Li*. Fluorescence turn-on sensing of protei based on mannose funtioalized perylee bsmides and its fluorescence imaging. Biosens. Bioelectron., 2014, 58, 27-32.

12) Ke-Rang Wang, Yue-Qng Wan, Hong-Wei An, Jin-Cao Zhang, Xiao-Liu Li*. A triazatruxen-based glycoclusters as a fluorescent sensor for Concanavalin A. Chm. Eur. J., 2013, 19, 2903-2909.

13) Ke-Rang Wang, Hong-Wei An, Ling, Wu, Jin-Chao Zhang, Xiao-Liu Li*. Ciral self-assembly of lactose functionalized perylene bisimides as multivalent glycocluster. Chem. Commun., 2012, 48, 5644-5646.

14) Ke-Rang Wang, Dong-Sheng Guo, Bang-Ping Jiang, Yu Liu*. Excitonic coupling interations in the self-assemby of perylene-bridged bis(beta-cyclodextrin)s and porphyrin. Chem. Commun., 2012, 48, 3644-3646.

15) Ke-Rang Wang*, Hong-Wei An, Yue-Qing Wang, Jin-Chao Zhang, Xiao-Liu Li*. Multivalent glycoclusters constructed by chial self-assembly of mannose functionalized perylene bisimide. Org. Bimol. Chem., 2013, 11, 1007-1012.

16) Ke-Rang Wang, Dong-Sheng Guo, Bang-Ping Jiang, Zhan-Hu Sun, Yu Liu*. Molecuar aggregtion behavior of perylene-bridged bis(beta-cyclodextrin)s and its electron interactions upon selective binding with aromatic guests. J. Phys. Chem. B, 2010, 114, 101-106.

17) Yu Liu*, Ke-Rang Wang, Dong-Sheng Guo, Bang-Ping Jiang. Supramolecular assembly of peryene bisimide with beta-cyclodextrin grafts as solid-state fluorescent sensor for vapor detection. Adv. Funct. Mater., 2009, 19, 2230-2235.

四、科研项目

1)国家自然科学基金(面上项目)：项目编号:21372059，起止时间:2014-2017，主持，结束。

2) 河北自然科学基金(优秀青年基金)：项目编号： B2016201254，起止时间：2016/01-2018/12，主持，结束.

3)国家自然科学基金(青年基金)：项目编号:2100202020，起止时间:2011-2013，主持，结束。

4)河北省自然科学基金:项目编号:B2011201052，起止时间:2011-2013， 主持，结题。

5)河北自然科学基金:多胺连接萘酰亚胺和二氯乙酰胺抗肿瘤化合物的合成和性质研究。项目编号:B201201041，起止时间:2012-2014，主持，结束。

6)河北省高校科技研究项目(优秀青年基金)：项目编号:YQ2013006，起止时间:2013-2015，主持，结束。