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Scientistshaveknownsince1952thatDNAisthebasicstuffofheredity.They'veknownitschemicalstructuresince1953.TheyknowthathumanDNAactslikeabiologicalcomputerprogramsome3billionbitslongthatspellsouttheinstructionsformakingproteins ,thebasicbuildingblocksoflife.
Buteverythingthegeneticengineershaveaccomplishedduringthepasthalf-centuryisjustapreambletotheworkthatCollinsandAndersonandlegionsofcolleaguesaredoingnow.CollinsleadstheHumanGenomeProject,a15-yearefforttodrawthefirstdetailedmapofeverynookandcrannyandgeneinhumanDNA.Anderson,whopioneeredthefirstsuccessfulhumangene-therapyoperations ,isleadingthecampaigntoputinformationaboutDNAtouseasquicklyaspossibleinthetreatmentandpreventionofhumandiseases.
Whattheyandotherresearchersareplottingisnothinglessthanabiomedicalrevolution.LikeSiliconValleypiratesreverse-engineeringacomputerchiptostealacompetitor'ssecrets,geneticengineersaredecodinglife'smolecularsecretsandtryingtousethatknowledgetoreversethenaturalcourseofdisease.DNAintheirhandshasbecomebothablueprintandadrug,apharmacologicalsubstanceofextraordinarypotencythatcantreatnotjustsymptomsorthediseasesthatcausethembutalsotheimperfectionsinDNAthatmakepeoplesusceptibletoadisease.
Andthat'sjustthebeginning.Forallthefeveredworkbeingdone ,however,scienceisstillfarawayfromtheBraveNewWorldvisionofengineeringaperfecthuman—orevenaperfecttomato.Muchmoreresearchisneededbeforegenetherapybecomescommonplace,andmanydiseaseswilltakedecadestoconquer,iftheycanbeconqueredatall.
Intheshortrun ,themostpracticalwaytousethenewtechnologywillbeingeneticscreening.DoctorswillbeabletodetectallsortsofflawsinDNAlongbeforetheycanbefixed.Insomecasestheknowledgemayleadtotreatmentsthatdelaytheonsetofthediseaseorsoftenitseffects.Someonewithageneticpredispositiontoheartdisease,forexample,couldfollowalow-fatdiet.Andifscientistsdeterminethatavitalproteinismissingbecausethegenethatwassupposedtomakeitisdefective ,theymightbeabletogivethepatientanartificialversionoftheprotein.Butinotherinstances,almostnothingcanbedonetostoptheravagesbroughtonbygeneticmutations.(409words)
1.ItcanbeinferredfromthetextthatCollinsandAndersonandlegionsofcolleagues_____.
[A]knowthathumanDNAactslikeabiologicalcomputerprogram
[B]havefoundthebasicbuildingblocksoflife
[C]haveaccomplishedsomegeneticdiscoveryduringthepasthalf-century
[D]aremakingabreakthroughinDNA
2.CollinsandAndersonarecitedinthetexttoindicateallthefollowingEXCEPTthat______.
[A]time-consumingeffortisneededtoaccomplishthedetailedmapofinhumanDNA
[B]humangene-therapyoperationsmaybeappliedtothepatients
[C]gene-therapynowisalreadygenerallyusedtothetreatmentandpreventionofhumandiseases
[D]informationaboutDNAmaybeusedinthetreatmentandpreventionofhumandiseases
3.Theword“pirate ”(line2,paragraph3)means______.
[A]onewhorobsatseaorplundersthelandfromthesea
[B]onewhomakesuseoforreproducestheworkofanotherwithoutauthorization
[C]totake(something)bypiracy
[D]tomakeuseoforreproduce(another'swork)withoutauthorization
4.Wecandrawaconclusionfromthetextthat_____.
[A]engineeringaperfecthumanisnotfeasibleforthetimebeing
[B]it‘simpossibleforscientiststoengineeraperfecttomato
[C]manydiseaseswillneverbeconqueredbyhumanbeings
[D]doctorswillbeabletocureallsortsofflawsinDNAinthelongrun
5.Thebesttitleforthetextmaybe______.
[A]DNAandHeredity
[B]TheGeneticRevolution
[C]ABiomedicalRevolution
[D]HowtoApplyGeneticTechnology
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