导师信息#兰州大学药学院导师介绍#薛伟华

姓名：薛伟华(男)
职称职务：副教授
电子邮箱：xuewh@lzu.edu.cn

1
、学习与工作经历

2003年9月--2006年7月在南京大学生物化学专业学习，获博士学位

2006年7月-2007年7月在加拿大阿尔伯特大学访问学习

2007年6月--2009年8月在海中国科学院上海有机化学研究所工作

2009年9月-现在在兰州大学工作

2、教学工作与成果

讲授分析化学和物理化学

3 、科研项目与成果

1.WeihuaXue,HuajiaDiao,XiChen,JiangningChenandJunfengZhang.Anefficientvectorforgenedelivery:α,β-poly(3-dimethylaminopropyl-D,L-aspartamide),EuropeanJournalofPharmaceuticsandBiopharmaceutics2007(66)327-333.

2.WeihuaXue,XiaoyunCheng,JianFan,HuajiaDiao,ChunmingWang,YiLuo,JiangningChenandJunfengZhang.Anovelstereoselectivesynthesisof1,2-trans-thioaldoses,TetrahedronLetter2007(48)6092-6095.

3.WeihuaXue,JiansongSunandBiaoYu.Anefficientrouteto2-amnio-β-galactosidesand-glucosidesviastereoselectiveMichaelAdditionof2-nitrogalactal.JournaloforganicChemistry2010(74)5079-5082.

4.WeihuaXue,*LifenZhang.AnImprovedandAlternativeMethodforthePreparationofPer(6-bromo-6-deoxy)cyclodextrins.Synthesis,2011,3612–3614

5.WeihuaXue,*LifenZhang.ANovelProtocolfortheRegioselectiveBrominationofPrimaryAlcoholsinUnprotectedCarbohydratesorGlycosides.ChinesejournalofChemistry,2012(30)1429-1432

6.WeihuaXue,*LifenZhang.B(C6F5)3asaHighlyEffectiveCatalystforthePhosphorylTransferReaction.ChinesejournalofChemistry,2012(30)1997-1800

7.XiaofengLiu,SenCheng,XiaoleiWang,WeihuaXue*.Aconvenientprocedurefortheformationofper(6-deoxyl-6-halo)cyclodextrinsusingthecombinationoftetraethylammoniumhalidewith[Et2NSF3]BF4.Synthesis,2013,45,3103-3105.

8.XiaolongYuan,SenCheng,YanbinShi,WeihuaXue*.Photocatalyticsynthesisofglycosylbromide.Synthesis,2014,331-335

9.LanYu,WeihuaXue,CuiLei,HongyuLi.Useofhydroxypropyl-β-cyclodextrin/polyethyleneglycol400,modifiedFe3O4nanoparticlesforcongoredremoval.Internationaljournalbiologicalmacromolecules.2014,64,233-239.

10.DaboPan,WeihuaXue,XiaotingWang,JingjingGuo,HuanxiangLiu,XiaojunYao.MolecularMechanismoftheEnhancedVirulenceof2009PandemicInfluenzaA(H1N1)VirusfromD222GMutationintheHemagglutinin:AMolecularModelingStudy.JournalofMolecularModeling,2012,18,4355-4366.

11.XiaoyunCheng,WeihuaXue,HuajiaDiaoandJunfengZhang.AntitumoractivityandtoxicologicalpropertiesofDoxorubicinconjugatedtoα,β-poly[(2-hydroxyethyl)-L-aspartamide]administratedintraperitoneallyinmice.AnticancerDrug2010(21)362-372.

4
、研究与招生方向

糖化学和糖生物学